Two cases of D-penicillamine-induced elastosis perforans serpiginosa

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D-penicillamine-induced Elastosis Perforans Serpiginosa

To the Editor: Elastosis perforans serpiginosa (EPS) is part of different kinds of perforating diseases that are dependent on factors such as idiopathic, reactive, or drug induced. We report here a case of a patient who presented with multiple reddish‐brown keratinized papules coalescing to form serpiginous plaques in the anterior and posterior of the neck, which was found to be typical D‐penic...

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Penicillamine induced pseudoxanthoma elasticum with elastosis perforans serpiginosa.

Long term D-penicillamine therapy, especially when used to treat Wilson's disease has been shown to cause elastosis perforans serpiginosa, pseudoxanthoma elasticum perforans and other degenerative dermatoses. We report a 23-year-old male patient who presented with multiple firm papules, nodules over the neck, axillae, front of elbows for five years. He was a known case of Wilson's disease on lo...

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Drug-induced elastosis perforans serpiginosa.

To cite: Menzies S, Kirby B. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/ bcr-2015-212482 DESCRIPTION A 42-year-old woman presented with a 5-year history of multiple enlarging skin lesions. Her medical history was significant for Wilson’s disease, for which she had taken penicillamine for approximately 20 years. She had multiple small erythaematous keratotic papul...

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Elastosis Perforans Serpiginosa

Elastosis perforans serpiginosa is a rare skin disease characterized by transepidermal elimination of abnormal elastic fibers. This condition classically presents as small papules arranged in serpiginous or annular patterns on the neck, face, arms, or other flexural areas. While these lesions may spontaneously resolve, they often persist for longer periods of time. Though numerous treatment mod...

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Elastosis perforans serpiginosa: a case of a penicillamine-induced degenerative dermatosis.

nated glove (4H) appears relatively impermeable toMMA,but widespreaduse is limitedby cost anddiminisheddexterity.2,3 Allergic contact dermatitis inducedbyMMAmay result in significant discomfort and is seen frequently after occupational exposure amongdentists, dental technicians, orthopedic surgeons, andotherhealthcareworkers. Second-andthirddigit fingertips are commonly involved.3 Nail dystroph...

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ژورنال

عنوان ژورنال: Indian Journal of Dermatology, Venereology, and Leprology

سال: 2016

ISSN: 0378-6323

DOI: 10.4103/0378-6323.178907